German troops take part in the destruction off the Warsaw Ghetto in 1943. The Warsaw Ghetto was the largest of all the Jewish ghettos in Nazi-occupied Europe during World War II. It was established by the Nazi German authorities between October and November 16, 1940; There were over 400,000 Jews imprisoned there. In April 1943, Nazi troops entered the ghetto. They systematically burned and blew up the ghetto buildings, block by block, rounding up or murdering anybody they could capture. Significant resistance ended on April 28,.