Human kidney aldehyde dehydrogenase 1A1 (ALDH1A1), molecular model. The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of endogenous and exogenous aldehyde substrates. ALDH1 has three main isotypes, ALDH1A1, ALDH1A2, and ALDH1A3.

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